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[演講] 4/10:陳倩瑜老師主講:當深度學習與生物資訊在個人全基因體註解相遇/When Deep Learning Meets Bioinformatics in Personal Genome Annotation

活動與演講
張貼人:網站管理員公告日期:2017-03-21
poster
臺大基蛋所Medical Genetics & Genomics Monthly Seminar邀請
 
[講題]:當深度學習與生物資訊在個人全基因體註解相遇
            When Deep Learning Meets Bioinformatics in Personal Genome Annotation
[講者]:陳倩瑜 教授 (CV詳如附件)
            臺大生物產業機電工程學系教授
[時間]:4/10(星期一) 上午 11:20-12:10
[地點]:醫學院基醫大樓 202講堂
[演講摘要]

Bioinformatics has played an important role in annotating the human genome since its draft was first announced in 2001. As the sequencing cost decreased dramatically owing to the advance of next-generation sequencing technology, the need of precisely annotating a personal genome is right around the corner. This talk will start with the success of using structural bioinformatics in predicting the influence of a single nucleotide variation on changing the protein-DNA binding affinity. Next, the concept of deep learning and how it has been used to annotate epigenomes and to explore the roles of cis-regulatory sequence variations will be introduced. As the scale and complexity of personal genomic data analysis increase rapidly, deep learning will definitely become one of the effective ways to associate personal genomic variations with diseases or drug responses. The current status and challenges of using deep learning in annotating personal genomes will be kindly addressed in the talk and it deserves more attentions when designing Bioinformatics education in the near future.

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最後修改時間:2017-03-21 PM 5:51

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